Biogen seeks FDA approval for Alzheimer’s drug; aims to be first to slow disease
By
Alicia Lasek
Jul 09, 2020
Treatment with aducanumab reduced declines in memory, language, and activities of daily living performance, the drugmaker says.
Delayed cognitive decline linked to daily use of two languages
By
Alicia Lasek
Sep 21, 2020
People receive a later diagnosis of mild cognitive impairment when they actively speak two languages every day, investigators report.
Elders get a cognitive boost after positive social interactions, mobile study finds
By
Alicia Lasek
Sep 15, 2021
In a smartphone-enabled study, adults aged 70 years and older had better cognitive performance the same day that they reported having more frequent, pleasant social interactions than usual — and on the...
First appropriate use guidance published for Alzheimer’s drug Aduhelm
By
Alicia Lasek
Jul 28, 2021
The new guidelines cover how to choose appropriate patients, safely scale up to a full dose, monitor side effects and assess effectiveness. The authors also address when to stop therapy and what patients...
Clinical Briefs for Tuesday, September 24
By
Alicia Lasek
Sep 23, 2019
Long-term study of nurses links nut consumption with improved health … Alzheimer’s vaccine performs well in phase 2 trial … Gum disease linked to higher risk of hypertension … Simple lifestyle...
U.S. lawmakers ramp up scrutiny of FDA following agency’s approval of controversial Alzheimer’s drug
By
Alicia Lasek
Sep 07, 2021
The FDA is being asked to help explain how Aduhelm (aducanumab) met accelerated approval criteria when so many experts — including internal advisers — have flagged insufficient safety and efficacy...
Algorithm accurately predicts Alzheimer’s risk, study finds
By
Alicia Lasek
May 05, 2020
A computer algorithm can go head-to-head with neurologists, accurately diagnosing Alzheimer’s disease and predicting risk, say investigators.
NIA set to build $300M ‘real world’ Alzheimer’s database
By
Alicia Lasek
Apr 06, 2023
The goal is to collect real-world data on Alzheimer’s disease and create a centralized data hub, helping to expand and speed Alzheimer’s research.
Gait speed slows long before dementia diagnosis, 15-year study finds
By
Alicia Lasek
Feb 11, 2022
Slowing gait speed may signal the onset of dementia up to nine years before cognitive decline becomes evident, investigators say. It’s also linked to Alzheimer’s-related brain changes.
Avoid antipsychotic use to lessen stroke risk in Alzheimer’s patients: study
By
Alicia Lasek
Oct 29, 2021
The increased odds of experiencing a stroke within 60 days of starting treatment suggests that even short-term antipsychotic use should be avoided if possible, investigators contend.