Dr. Karel Kostev
Karel Kostev, Ph.D.

Researchers have found that antihypertensive drug use is tied to a lower incidence of dementia in elderly patients followed in German general practices.

In a study to be published in the next issue of the Journal of Alzheimer’s Disease, researchers included more than 12,000 patients aged 60 years and older who had received a diagnosis of dementia from their general practitioners between 2013 and 2017. They were matched to control subjects without dementia by age, sex, diagnosis year and co-diagnoses.

The use of antihypertensive drugs, including angiotensin II receptor blockers, angiotensin-converting enzyme inhibitors, calcium channel blockers and beta blockers was found to be associated with decreased dementia incidence, wrote lead author Karel Kostev, Ph.D.