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The antidepressant Paxil has shown promise in strengthening the heart, new research suggests. In a discovery that University of Michigan researcher John Tesmer, Ph.D., described as “completely serendipitous,” the drug paroxetine, a.k.a. Paxil, inhibits G protein-coupled receptor kinase 2. That’s a protein that becomes over-expressed when people have heart failure. The study was published online in ACS Chemical Biology.